ncRNA name | MMP-9 siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Rattus norvegicus |
Tissues/Cell_line | retinal Müller cells (RMCs) |
Methods | siRNA transfection, flow cytometry, MTT assay, qRT-PCR, Western blot |
Expression pattern | associated |
Functional description | The cell viability of siRNA-MMP9 group was significantly increased while decreased in MMP9 overexpression group when compared to control group, respectively. The apoptotic cells in MMP9 overexpression group significantly increased while decreased in siRNA-MMP9 group when compared with control group. |
PubMed ID | 26617754 |
Year | 2015 |
Title | Apoptotic effect of mtrix metalloproteinases 9 in the development of diabetic retinopathy. |
Drug-related ncRNA | NO |
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